The Background of Circular RNA Synthesis
In recent years, nucleic acid therapy involving various types of ribonucleic acids (RNAs), including messenger RNA (mRNA), small interfering RNA (siRNA), and microRNA (miRNA), has rapidly emerged as a new cornerstone of modern medicine. Among them, the mRNA-based vaccines developed, particularly the COVID-19 vaccine, have played a significant role in combating the novel coronavirus (SARS-CoV-2)…
Strategies and Challenges for the Next Generation of Antibody-Drug Conjugates
Antibody-drug conjugates (ADCs) have revolutionized the field of targeted cancer therapy by combining the specificity of monoclonal antibodies with the potency of cytotoxic drugs. ADCs have shown remarkable clinical success, leading to several FDA-approved therapies. However, the development of the next generation of ADCs presents new strategies and challenges that must be addressed to improve efficacy,…
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ADC Cleavable Linker: Classification and Mechanism of Action
Antibody-drug conjugates (ADCs), as emerging anticancer drugs, can deliver highly cytotoxic molecules directly to cancer cells to kill them. ADC is a monoclonal antibody covalently bound to cytotoxic chemical substances (payload) through linker. ADC linker plays a key role in the therapeutic effect of ADC, and its characteristics greatly affect the therapeutic index, pharmacodynamics and pharmacokinetics…
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Fermentation Production of ADC Payloads
Targeted therapies have significantly advanced the field of cancer therapy, and among these, antibody-drug conjugates (ADCs) have emerged as a viable therapeutic strategy. ADCs increase efficacy and decrease systemic toxicity by fusing the potency of cytotoxic drugs with the specificity of monoclonal antibodies (mAbs). The manufacture of high-quality and stable payloads by fermentation techniques is…
Canon Printer Won’t Connect to WiFi Troubleshooting and Solutions
With the rise of wireless connectivity, printers have embraced the convenience of connecting to WiFi networks, making printing tasks more flexible and efficient.
From Local to Global: Mastering the Exporting Game
The Basics of Exporting: A Step-by-Step Guide Exporting offers tremendous opportunities for businesses to expand their reach and tap into global markets. However, it can also be a complex process that requires careful planning and execution. In this step-by-step guide, we will walk you through the basics of exporting and help you navigate the journey…
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UNVEILING THE ALLURE OF FASHION: A TIMELESS JOURNEY OF SELF
Mismatched Outfits, a creative realm where becomes art, threads weave stories, and style becomes a language of self-expression. Through the ages, fashion has been an ever-evolving entity, reflecting the cultural shifts, social norms, and individual identities of its time. From the extravagant courtly attires of the past to the contemporary streetwear revolution, fashion has continuously…
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What is JetBlue Flight Cancellation & 24 Hour Cancellation Policy?
When you reserve your flight through JetBlue Airlines, you must familiarize yourself with JetBlue Airlines policies. One of the most important policies of JetBlue is flight cancellation. However, canceling the airline ticket may appear to be a difficult task at times, but once you understand the policy and its rules, it will be simple. Therefore…
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JVT Infotech – Best Affiliate Marketing Company
JVT Infotech company is a business that specializes in connecting advertisers with affiliate marketers to promote products or services. The JVT Infotech acts as an intermediary between advertisers and affiliates, facilitating partnerships and providing the necessary tools and resources for successful affiliate marketing campaigns. Here are some key aspects of an JVT Infotech: Affiliate Network: JVT…
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